20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9138 | Indirubin-3′-oxime | Indirubin-3'-monoxime | GSK-3 , CDK , JNK |
Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease. | |||
T16886 | Sinefungin | Adenosyl-Ornithine,A-9145,Antibiotic 32232RP | Others , Histone Methyltransferase , Antibiotic , Antifungal |
Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates r... | |||
T2769 | 3-Aminopropionitrile fumarate (2:1) | Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate | Others |
3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) is an organic compound and antirheumatic agent used in veterinary medicine. | |||
T4S0498 | Glaucocalyxin A | Wangzaozin B,Leukamenin F | Apoptosis , Akt , Caspase , PI3K |
1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi... | |||
TN1254 | 3'-Methoxydaidzein | Sodium Channel | |
3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 nM, respectively. 3'-Methoxydaidzein was specific for colla... | |||
TN6495 | 3,4-O-dimethylcedrusin | ||
3′,4-O-Dimethylcedrusin can improve wound healing in vivo by stimulating the formation of fibroblasts and collagen. | |||
TP2362 | Acetyl decapeptide-3 | Rejuline,Ac-tyr-arg-ser-arg-lys-tyr-thr-ser-trp-tyr-NH2 | |
Acetyl decapeptide-3 is a peptide that can stimulate collagen and elastin to increase skin elasticity and increase cell growth and improve healing and repair. | |||
T60303 | Collagen-IN-1 | ||
Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Coll... | |||
TN5661 | 1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one | ||
1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood. | |||
T61811 | GPVI antagonist 3 | ||
GPVI antagonist 3 (Compound 2) is a potential antagonist that shows promising antiplatelet activity by selectively inhibiting the interaction between the Glycoprotein VI (GPVI) receptor and its ligands. It demonstrates p... | |||
T36929 | Pal-KTTKS (acetate) | ||
Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when use... | |||
T82780 | Caprooyl-tetrapeptide-3 acetate | ||
Caprooyl-tetrapeptide-3 acetate, employed for diminishing fine lines and wrinkles, enhances collagen VII and laminin-5 expression in corticoid-induced skin aging models [1]. | |||
T12585L | PXS-5153A monohydrochloride | PXS-5153A monohydrochloride (2125956-82-1 free base) | Others |
PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 6... | |||
T36101 | Psychotridine | ||
Psychotridine is an alkaloid that has been found inP. forsterianaand has diverse biological activities.1,2,3It inhibits ADP-, collagen-, or thrombin-induced aggregation of washed isolated human platelets with IC50values ... | |||
T41079 | MMP13-IN-2 | MMP13-IN-2 | |
MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over... | |||
T38363 | MeOSuc-AAPV-pNA | ||
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neut... | |||
T36845 | Isogarcinol | ||
Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 μM) and suppres... | |||
TN4490 | Manassantin B | ERK , BCL , p38 MAPK , TNF , NF-κB , JNK , STAT , Antifection | |
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleu... | |||
T81592 | Osteostatin | PTHrP (107–111) | |
Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting with bone defects and exhibits efficacy in mitigating bone e... | |||
T35695 | Oleic Acid-13C | ||
Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been fo... |